Karen Eilbeck, Andy Brass, Norman Paton, Charlie Hodgman
Abstract
Motivation: Protein-protein
interactions provide vital information concerning the function
of proteins, complexes and networks. Currently there is no widely
accepted repository of this interaction information. Our aim is
to provide a single database with the necessary architecture to
fully store, query and analyse interaction data.
Results: An object oriented database has been created which provides scientists with a resource for examining existing protein-protein interactions and inferring possible interactions from the data stored. It also provides a basis for examining networks of interacting proteins, via analysis of the data stored. The database contains over a thousand interactions.